TACGEN
Phone: (877) 369-5430
(510) 334-9669
Email: info@tacgen.com

Epigenetic Modulator Discovery

Epigenetic modifications, including histone modifications and DNA methylation, have effect on gene expression and regulation. Epigenetics modulators affect chromatin modification by modulating modifying enzymes and then recruting transcription factories. TACGen provides services for epigenetic modulator discovery at three level, whole genome, specific gene locus and general epigenectic modulator screening in vitro and in vivo.

DNA Methylaton Profiling

DNA methylation and demethylation is involved in chromosome condnesation and decondensation and epigenentic reprogramming of genes. TACGen provides DNA methylation whole genome mapping, specific gene locus validation and general high throughput epigenetic modulator screening in vitro and in vivo.

Histone Modification Profiling

Histone modifications are involved in transcriptional regulation, chromatin condensatio, DNA repair and replication processes. TACGen provides high-throughput histone modification whole genome mapping, specific gene locus validation and general high throughput epigenetic modulator screening in vitro and in vivo.
    Histone Modifications Residue Modified Targets
    Acetylation 1 K-ac H3, H4, H3K9, H3K14, H3K18, H3K23, H3K56, H4K5, H4K8, H4K12, H4K16
    Methylation(K) K-me1 K-me2 K-me3 H3K4, H3K9, H3K27, H3K79
    Methylation(R) R-me1 R-me2a K-me2s H3R2, H317, H4R3
    Phosphorylation S-Ph, T-Ph H2AX, H2B, H3S10, H3S28, H3-T11
    Ubiquitylation K-ub H2A, H2B, H2AK63, H2AXK63
    Sumoylation K-su H2, H4, H2AK63, H2AXK63
    ADP-ribosylation E-ar H1, H3

Sample Submission:

  • Cell
  • Chromatin
  • ChIP antibody

Additional Services:

  • ChIP only services

Place Order:

  • Get a Quote
  • Send your samples
    • For customers located in SF Bay Area, TACGen will pick up the samples at your lab. Please Schedule Pick Up
    • For other customers, please use FedEx or UPS ship your samples to TACGen
      • TACGen's shipping address:
        TACGen
        15501G SAN PABLO AVE #362
        RICHMOND, CA 94806-5809

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Phone: US Toll Free (877) 369-5430 or (510) 334-9669    Fax: (510) 619-9534    Email: info@tacgen.com
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